Basic parameters

INCI Name	Urea
Chemical Name	Urea / Carbamide
Chemical Formula	CO(NH₂)₂
Purity	≥99,9%
Solubility	Completely soluble in water
Standard	Ph. Eur.
CAS Number57-13-6	57-13-6
Form	Crystalline powder
Colour	White
pH	7,5-9,5

Technical parameters – pharmaceutical urea Ph. Eur. CO(NH₂)₂

Granular cosmetic urea (also known as carbamide) is available as a pure, white crystalline powder with high water solubility. It is a raw material with predictable characteristics that facilitates precise dosing and ensures the reproducibility of each production batch. To streamline the supplier verification process, we have prepared a complete documentation package—the SDS/MSDS safety data sheet and current certificates of analysis (CoA) are available for download upon request.

Available packing

Bags 25kg

Cosmetic urea – MEDICOS distributor is your partner in industrial supply

As a boutique distributor, we supply Ph. Eur. grade urea to key players in the Polish market: from cosmetics and dermocosmetics manufacturers, through pharmaceutical companies, to specialized R&D laboratories and podiatry clinics. By choosing to work with MEDICOS, you gain not only a pure raw material of assured quality, but above all, operational safety.

Who is cosmetic urea for?

Cosmetics and dermocosmetics manufacturers
Pharmaceutical companies
Podiatry clinics and companies
Cosmetics and R&D laboratories
Manufacturers of dermatological preparations

Certificates and approvals

The raw material is completely GMO-free and comes with a full set of quality documentation (TDS, SDS, CoA, and regulatory declarations), which guarantees a smooth audit process even for products with the highest quality standards. Do you need documents for verification? Contact us—we will send you the complete documentation.

General information

Quality and Certifications

At MEDICOS, we control the quality of the raw material at every stage—from manufacturer selection, through the storage process, to the moment of delivery to your facility. We deliver not only the product, but above all the assurance that every batch meets stringent pharmaceutical and cosmetic standards.

Compliance with GMP and Ph. Eur.

The urea available from MEDICOS is manufactured in accordance with GMP (Good Manufacturing Practice) standards and is fully compliant with the requirements of the European Pharmacopoeia (Ph. Eur.). This guarantees absolute reproducibility of physicochemical parameters, eliminating the risk of non-compliance in formulations.

Certificate of Analysis (COA)

We include a detailed Certificate of Analysis (COA) with every shipment. This serves as the batch’s “identity card,” containing data on purity and composition. This ensures a precise match with your formulation.

SDS/MSDS Safety Data Sheet

The operational safety of your team and compliance with health and safety regulations are our top priorities. We provide a complete SDS/MSDS with key information.

Application

Industry	Examples for use
Cosmetics	products for dry and problematic skin (creams, lotions, foot and hand care products, dermocosmetics)
Pharamaceuticals	dermatological preparations (active ingredient), semi-solid formulations (excipient)

Applications of pharmaceutical urea

Pharmaceutical urea is a popular active moisturizing ingredient, commonly used as a component in creams designed for dry skin care. As a natural humectant in cosmetics, a component of NMF (Natural Moisturizing Factor), it ensures excellent skin tolerance and high efficacy, regardless of the complexity of the formulation.

Urea for cosmetics and dermocosmetics

In daily skincare, cosmetic urea acts as a key humectant that binds water in the epidermis and improves the skin’s protective barrier. It is a standard ingredient in moisturizing creams, serums, and body lotions. At concentrations of 2–10%, it supports the skin’s physiological balance, giving products the softness and elasticity consumers desire without causing excessive exfoliation.

Urea for podiatry

In podiatric formulations, pharmaceutical-grade urea is a specialized ingredient. Used in concentrations of 10–25%, it exhibits strong softening properties, helping to combat calluses and cracks on the feet. Thanks to the high purity of our raw material, podiatric preparations remain stable and effective, providing relief to patients with hyperkeratosis.

Urea in dermatological products

Urea in dermatological preparations is indispensable in supportive therapy for the treatment of eczema, psoriasis, or extreme skin dryness. At high concentrations (10–40%), it exhibits intense keratolytic activity, helping to remove dead skin cells. By using the raw material from our distribution, you create safe and effective solutions for the most demanding customers.

Urea for the pharmaceutical industry

As a supplier aware of industry standards, we offer Ph. Eur. urea that meets the strict standards of the European Pharmacopoeia. Compliance with GMP (Good Manufacturing Practice) ensures that this raw material can be safely used as an active or excipient ingredient in advanced pharmaceutical formulations. We guarantee purity and documentation that passes verification in drug registration processes without issue.

Downloadable materials

Detailed technical and regulatory documentation for the product is available from MEDICOS on request. To receive it, please send us an e-mail. We will send you a complete set of current quality and regulatory documents.

Technical support

We provide technical support at every stage of working with the raw material—from selecting the right material for the intended application, through application recommendations, to support during testing and implementation. We assist in interpreting technical data, physicochemical properties, and regulatory aspects of the raw material. As part of our collaboration, we offer basic formulation consulting and support in solving typical application problems, in cooperation with the raw material manufacturer.

Additional information

Pharmaceutical Urea – A Standard That Eliminates Risks in Formulations

Urea Ph. Eur. is a synthetic organic substance used as an active or functional ingredient in creams and ointments of the highest purity. By choosing urea for pharmaceuticals and modern cosmetics from MEDICOS’ distribution, you can be confident that your products will meet rigorous quality standards (Ph. Eur. and USP) right from the ingredient selection stage.

Production conducted in full compliance with GMP guarantees the reproducibility of each batch, which in practice eliminates surprises during production scaling or quality control of the finished product.

Chemical composition, purity, and origin of the raw material

Our pharmaceutical urea is high-purity carbamide (CO(NH₂)₂), produced entirely synthetically through a rigorously controlled process. Unlike technical-grade products, our urea Ph. Eur. is a pure monosubstance—completely free of processing aids, solvents, or inhibitors found in ureas intended for agricultural use.

We ensure that the urea we offer—as an active moisturizing ingredient—meets the strictest clean beauty standards and pharmaceutical requirements. We declare that the product:

is fully vegan, free from GMOs and animal-derived ingredients,
contains no formaldehyde, formaldehyde donors, parabens, or preservatives,
is free from microplastics, nanoparticles, silicones, and mineral oils,
contains no PEG, phthalates, or organohalogen compounds.

It is a safe humectant for cosmetics production that allows for the creation of a “clean” formulation without the risk of cross-contamination.

Stability and physicochemical properties

By choosing pharmaceutical-grade urea from MEDICOS, you are opting for a raw material with exceptional chemical stability, which directly translates to the safety and shelf life of the final product. Urea is a proven humectant for cosmetic production, characterized by very good water solubility and stability across a wide pH range. In practice, this allows for great flexibility in designing preservative systems and active ingredients in the aqueous phase.

Our urea Ph. Eur. has a neutral sensory profile and is completely odorless, so it does not affect the fragrance composition of the finished product. Its high hydrophilic properties and low molecular weight make it an extremely effective active moisturizing ingredient, essential where deep penetration and efficacy matter—especially when developing advanced dermocosmetics or using urea in dermatological formulations.

Technological functions of pharmaceutical urea

Our urea Ph. Eur. (carbamide) is a versatile ingredient for creams, whose effects depend on the concentration used:

moisturizing (2–10%) – works well as an intensive humectant in cosmetics. It binds water in the epidermis and strengthens the skin’s protective barrier,
exfoliation (>10%) – exhibits strong keratolytic activity. It is effective in podiatric products and specialized dermatological formulations.

Pharmaceutical-grade Urea (Ph. Eur.)

INCI name: Urea

CAS number: 57-13-6

Cosmetics

Pharmaceuticals

Dermatological products

Podiatry

Discover our offer

Raw materials used in cosmetics

Sorbitol T (E420)

INCI name:

Sorbitol

CAS no:

50-70-4

Food and dietary supplements

Pharmaceuticals

Cosmetics

Details

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Pharmaceutical Urea – Frequently Asked Questions

We know that selecting a raw material is a process that requires hard data and regulatory certainty. Below, we have compiled answers to key questions that will help you assess the suitability of our urea for your formulations and procurement processes.

Have more questions? Contact us for samples and test urea in your formula.

The main difference lies in its rigorous chemical purity and the absence of impurities typical of industrial products. Pharmaceutical-grade urea is a pure monosubstance free of processing aids and inhibitors, manufactured to GMP standards. It ensures full batch-to-batch consistency and stability, which ordinary technical-grade urea cannot guarantee.
As a specialized supplier, MEDICOS offers Ph. Eur.-grade raw material with nationwide delivery. We ensure continuous supply and full consulting support during the implementation of the raw material into production. What is the composition of pharmaceutical urea?

Our product is high-purity carbamide (CO(NH₂)₂) obtained synthetically, which guarantees the absence of GMOs and ingredients of animal origin. It is a vegan product, free from formaldehyde, parabens, microplastics, and mineral oils. This makes it a safe active moisturizing ingredient for modern, “clean” formulations.
For advanced formulations, the crystalline powder form works best due to its excellent solubility in water. Although granular cosmetic urea is sometimes found on the market, the fine crystalline form ensures faster processing and makes it easier to obtain clear solutions. Choosing the granular form minimizes the risk of uneven concentrations in the cosmetic formulation.
As an ingredient in creams, urea is typically used in concentrations ranging from 2% to 30%. In moisturizing products (humectants), the standard is 2–10%, while in specialized formulations, concentrations exceed 10%. Precise dosing depends on the product’s intended use—ranging from light emulsions to intensive preparations with keratolytic action.
Yes, its high purity and pharmacopoeial standard make it an ideal urea for dermocosmetics and podiatry. Its hydrophilic properties and low molecular weight support the treatment of eczema, psoriasis, and severe foot calluses. Safety of use in these areas is confirmed by numerous dermatological studies and the raw material’s high biocompatibility.
MEDICOS provides a complete package of quality documentation for each batch of raw material. A current COA (Certificate of Analysis) confirming the physicochemical parameters and an SDS/MSDS safety data sheet containing health and safety guidelines are standard. Upon request, we also provide regulatory declarations regarding origin, GMO status, and confirming the absence of prohibited substances.